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Intranasal delivery of Berberine via in situ thermoresponsive hydrogels with non-invasive therapy exhibits better antidepressant-like effects

AOD9604 and Cartilage Biology Research In a collagenase-induced knee osteoarthritis rabbit model, intra-articular injection of AOD9604 significantly enhanced cartilage regeneration compared to saline controls, with combined AOD9604 and hyaluronic acid injections proving more effective than either treatment alone producing superior morphological and histopathological scores and a significantly shorter lameness period in the AOD9604 + HA group

But I do find it interesting to consider preliminary findings like this and how they might relate to effectiveness of various types of treatment

852 RNA-seq analysis showed significant enrichment of signaling pathways related to mitochondrial autophagy and ferroptosis in human umbilical vein endothelial cells (HUVECs) incubated with NETs