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Federal Trade Commission (FTC) charged a chelation-advocacy group, the "American College for Advancement in Medicine" (ACAM), with making false or unsubstantiated claims when they promoted chelation therapy for heart disease on their website and on a brochure they published

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Glucagon receptor activation increases energy expenditure through thermogenesis, enhances fat oxidation and breakdown, improves overall metabolic rate, and provides additional appetite regulation through central nervous system effects

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