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Comparado con insulina basal aislada, la combinacin de lixisenatida ms insulina determina una reduccin significativa de la HbA1c, junto a una disminucin tambin significativa de la dosis de insulina administrada, tanto en trminos absolutos como en unidades por kilogramo de peso
A meta-analysis evaluating GLP-1 RAs, including exenatide and liraglutide, found these agents more effective in reducing both SBP and DBP compared to insulin and other oral antidiabetics, providing additional cardiovascular benefits [86]
2024;403(10434):e21-e31
But the drug, like so many Rx treatments, can still be expensive
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