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In its reduced state, glutathione is "ready for work." It has an extra electron that it can give away to neutralize a free radical
Phytochemicals such as, the Resveratrol (3,4,5-trihydroxy stilbene) and the Curcuminoids (with , -unsaturated carbonyl groups) are potential inducers of HO-1 expression through Nrf2/ antioxidant-responsive element (ARE) pathway 471,472
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