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Based mainly on receptor transcript expression in the nodose ganglia, where the cell bodies of vagal afferents reside, and nerve transection studies, endogenous gut hormones including ghrelin [23], cholecystokinin (CCK) [24, 25], GLP-1 [26], and peptide YY 336 (PYY 336 ) [27] are thought to control food intake via their interaction with vagal afferents in a paracrine manner

Request clinical or user trial data demonstrating efficacy in brightening, reducing dark spots, and improving skin texture

This can lead to side effects such as dizziness caused by low blood pressure

GI intolerance with GLP-1 RA use is a big deal