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Description

Structural and pharmacologic data indicate that the Nle4, DPhe7 substitutions in afamelanotide increase MC1R affinity and cAMP potency (added ligandreceptor interactions), while the receptors intracellular and extracellular loops contribute to Gs engagement and ligand selectivity

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We have organized political actions leading toward local and national mass mobilizations on racism, self-determination, reparations, quality health care, housing, criminal justice, and education

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Pownall, H

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