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Furthermore, a recent clinical study in women with obesity treated with semaglutide showed improved recognition of basic tastes, altered gene expression in the tongue (measured by tongue biopsy), decreased activation of putamen in response to calorie-dense sweet and savory food cues, and increased cortical brain activity in response to the sweet taste stimulus compared to placebo

Sugiarto, D

They also had significantly lower levels of weekly alcohol craving throughout the trial

Reduced risk of gastrointestinal discomfort: Many individuals prefer slower escalation to minimize temporary nausea, bloating, or appetite fluctuations