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Tumor-associated fibroblasts secrete cytokines such as TGF- and IL-6, which activate NOX2 in monocytes, thereby increasing O production

Antioxidant Defense: Glutathione serves as the first line of defense against oxidative stress, which is known to contribute to the aging process and various diseases

Ordonez-Gutierrez L, Wandosell F (2020) Nanoliposomes as a therapeutic tool for Alzheimers disease

Both exercise and dietary interventions have been shown to increase GSH levels, particularly moderate exercise (versus vigorous exercise) and consumption of cruciferous vegetables.Additional therapies include resveratrol, selenium, whey protein, lipoic acid,pycnogenol,spirulina,silymarin,and sulforaphane