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Contact your healthcare provider if you experience: Bruises larger than two inches in diameter or that continue expanding after 24 hours Severe pain at the injection site that interferes with daily activities or doesn't improve within 48 hours Signs of infection including increasing warmth, redness spreading beyond the immediate injection site, purulent drainage, or fever above 100.4F (38C) Bruising that persists beyond three weeks without improvement Development of a hard lump or nodule beneath the skin that doesn't resolve Sudden increase in bruising frequency or severity compared to your usual pattern Bruising accompanied by unusual bleeding from other sites (gums, nose, or in urine/stool) Patients taking anticoagulant medications require particular vigilance

Emerging agents like tirzepatide and orforglipron demonstrate the expanding horizon of GLP-1-based therapies, offering enhanced efficacy and novel mechanisms of action

Physical examination checks range of motion, muscle tenderness, and nerve function

Losing employer coverage for an expensive medication you depend on is stressful, but it is not the end of the road