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It could be that apparently healthy people who report benefits may have undiagnosed B12 deficiency

One Phase 2 trial of lixisenatide in Parkinsons did meet its primary motor endpoint, the biology of GLP-1 in the brain is real, and questions remain about earlier intervention, specific subpopulations, and whether vascular or metabolic contributions to neurodegeneration might still respond

418 Bipolar disorder (BP) Both the total number of glial cells and astrocytic densities are substantially (up to 40%) decreased in the post-mortem BP tissues, whereas numbers of neurones are not changed