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There can be many reasons for this: They may take other medications that can cause weight gain, they may have altered microbiota bacteria affecting their digestive system or they may have a genetic background that causes it to be harder to lose weight

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Additionally, the selectivity of H 2 S donors, individual differences among patients, interactions with other therapeutic modalities, and potential side effects need to be further investigated in future research

Metformin is a biguanide drug that decreases blood glucose by reducing glucose production in the liver, decreasing intestinal absorption, and increasing insulin sensitivity of target tissues