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Some individuals may also experience decreased appetite, suppressed food cravings, and improved mood

Preemptive education will eliminate unnecessary alarm and premature discontinuation. Pharmacists should also reinforce the start slow and go slow titration schedule to mitigate gastrointestinal distress

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These findings provide compelling evidence in support of the hypothesis that GLP-1 RAs inhibit glucagon secretion by stimulating the release of somatostatin, an effect that is independent of insulin and the secretory products of -cells