123 Besides, oxidative stress conditions also increase the innately high IDH1 expression, and IDH1 silencing significantly enhances cell sensitivity to cancer chemotherapy, radiotherapy, and photodynamic therapy by reducing NADPH
melanogaster, DmGSTS1-1 exhibited glutathione peroxidase activity towards cumene hydroperoxide (CHP, oxidative stress inducer)
This can be a normal part of how the cycle changes over time
Se deficiency negatively impacts immune cells during activation, differentiation, and proliferation through redox signaling, oxidative burst, calcium flux, and the subsequent effector functions of immune cells (Huang et al., 2012