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The nail plate is a very hard tissue that is difficult to cut, and this often leads to tractional artefacts, epithelial detachments, and, ultimately, a poor orientation of the cut, thereby hindering interpretation.3,7,10,11,16 There are different methods for softening the nail piece before cutting,3,911,13,31 but these are outside the scope of the present article

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These unstable molecules can damage cells and contribute to ageing

Observed side effects in research environments are generally mild and temporary, most commonly including: Temporary fatigue-related observations Mild fluid-retention variability Increased hunger- or appetite-related observations Mild headache-related observations Minor administration-site irritation such as redness or temporary administration-site sensitivity observations Proper reconstitution, sterile handling practices, proper administration techniques, and regular administration-site rotation are important for minimizing local irritation and maintaining peptide stability and consistency during research use