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Badger TM, Huang J, Ronis M, Lumpkin CK: Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high
Decreased GSH then results in lipid peroxide accumulation and induction of ferroptosis
This allows the product to be supplied in multi-dose vials and used for repeated withdrawals, in contrast to preservative-free sterile water which is intended for single use only
Too much methionine can lower both Hcy and GSH, leading to more free radicals and damage to DNA, RNA, and mitochondria
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