Like many B vitamins, vitamin B12 acts as an enzymatic cofactor for essential functions of the body (1)
As part of the antioxidant defence system, GSH participates in conjugation reactions catalyzed by glutathione-S-transferases (GSTs), in the reduction of hydrogen peroxide (H O ) and lipid hydroperoxides (LOOH) catalyzed by glutathione peroxidases (Gpxs), and the reduction 2 2 of protein-disulfi des (PrSSG) catalyzed by glutaredoxins (Grxs)
However, it should be noted that the levels of GPx and SOD were also higher in AD cases, although the observed difference was not statistically significant (110)
Imaki T, Shibasaki T, Shizume K, Masuda A, Hotta M, Kiyosawa Y, et al