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We also quantified metabolites involved in the most proximal stages of the glycolysis pathway, namely glucose-6-phosphate (G6P) and fructose-6-phosphate (F6P) ( Figures 5H, I)
Mechanism of Action (How DSIP Works) CNS Penetration: Crosses the blood-brain barrier, exerting central effects on sleep regulation [Graf 1981]
Potential mild effects observed in animal and in vitro models include transient fatigue, mild nausea, or digestive discomfort related to metabolic acceleration
9 Materials and methods A structured literature review (PRISMA 2020) was conducted across PubMed, Embase, Cochrane Library, Scopus, and Google Scholar to 31 January 2026
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