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Figure 2 The gut-derived incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are responsible for the so-called incretin effect (i.e., the potentiation of glucose-stimulated insulin secretion after meal ingestion) (26)
In future RCTs, key considerations such as the optimal timing of intervention, treatment duration, specific patient subgroups based on molecular diagnosis, and potential systemic adverse events require further investigation
Diabetes 72 , 17191728 (2023)
This flexibility is useful but introduces another potential error point
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