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Indeed, as it will be discussed below, serious concerns had been repeatedly raised on the actual PAC safety (Roberts et al., 2016), Glutathione Levels and COVID-19 An interesting breakthrough in the comprehension of COVID-19 pathogenesis may derive from three independent articles published between April and May 2020 pointing to the importance of reduced glutathione (GSH) cellular levels and integrity of the related antioxidant routes in COVID-19 pathogenesis (Polonikov, 2020

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