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Surprisingly, another study showed that diabetes-related cardiovascular autonomic damage is first manifested in the vagus nerve (106), which may involve a ferroptosis-mediated overall decrease in parasympathetic tone, ultimately leading to over-activation of the sympathetic nerve and the worsening development of metabolic complications
We have identified iron accumulation and lipid peroxidation during this process
Additionally, it attenuated collagen-1 (hepatic fibrosis markers), -SMA, triacylglycerols and total cholesterol in CCl4-induced liver fibrosis in obese ob/ob mice [47]
Saris, A
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