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These two pathways cooperate in several ways: IFN-I generated by cGAS-STING heightens NLRP3 sensitivity, and NLRP3-dependent IL-1 upregulates cGAS via NF-KB, creating a positive-feedback loop
Medinos data shows these complaints are common enough that simple, repeatable measures usually resolve them without stopping therapy
Bradley Layton are or were employees of RTI Health Solutions, which received research funding for this study from Bayer
doi: 10.1097/JOM.0000000000002296
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