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Most patients follow a gradual dose escalation schedule to reduce side effects and improve long-term tolerance

This is because after this period, the bacteriostatic preservative can no longer prevent contamination, often leading to a compromised product that can put the patients at risk

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This review consolidates the pivotal role of ferroptosis in exacerbating ischemic stroke pathology, driven by iron dysregulation, lipid peroxidation, and mitochondrial collapse