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Since 2016, Aspergillus fumigatus (associated with a mortality rate of 50%90%), Cryptococcus neoformans (20%70%), and Candida albicans (20%40%) have been recognized as the leading causes of life-threatening fungal infections (Vandeputte et al., 2012

Importantly, the QMP-engineered GLP-1 albumin fusion did not only display improved PK properties, but also demonstrated a prolonged therapeutic effect in healthy human FcRn Tg32 mice challenged with a high dose of glucose

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Routes reported in the literature include intravenous, subcutaneous, and intraperitoneal administration in animal models, with intravenous infusion common in the early human studies