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What to Do If You're Taking GLP-1s and Oral Birth Control If you're currently taking a GLP-1 medication and oral birth control pills, here's your action plan: If You're Taking Tirzepatide (Mounjaro/Zepbound): Use backup contraception (condoms) for 4 weeks when starting and 4 weeks after each dose increase Consider switching to an IUD, implant, ring, patch, or Depo shot for more reliable protection Talk to your provider about the best long-term contraception strategy If You're Taking Other GLP-1s (Ozempic, Wegovy, Saxenda, Trulicity): Continue your birth control as prescribed Use backup contraception (condoms) if you're experiencing significant nausea or vomiting Consider non-oral options for added peace of mind, especially if you have PCOS or fertility concerns If You're Taking Rybelsus (Oral Semaglutide): Take Rybelsus on an empty stomach as directed Space out your birth control pill by several hours before or after taking Rybelsus Set phone reminders to help you remember the timing Consider switching to a non-oral contraceptive to avoid the hassle Best Birth Control Options While on GLP-1 Medications Based on effectiveness, convenience, and lack of drug interactions, here are my top recommendations: Highly Effective, No Interaction with GLP-1s: Hormonal IUD (Mirena, Kyleena, Skyla, Liletta) - lasts 3-8 years Copper IUD (Paragard) - lasts 10 years, no hormones Arm implant (Nexplanon) - lasts 3 years Depo-Provera - injection every 3 months Good Options with No Interaction: NuvaRing - monthly vaginal ring Birth control patch - weekly patch Requires Extra Attention: Birth control pills - need backup contraception with tirzepatide