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Role of GLP-1R binding kinetics The length of time that an agonist remains bound to its receptor, or residence time, is an important factor influencing the duration of drug action and a suggested driver of sustained signaling from internalized receptors 7
The most common are nausea, vomiting and constipation, which are usually mild and temporary
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Starting GLP-1 therapy represents a significant step in managing diabetes or obesity, and understanding what to anticipate helps ensure realistic expectations and optimal outcomes
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