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As the number of people using semaglutide drugs rises, more people may be at risk for this dangerous type of blood clot

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Unlike endogenous GLP-1, which has a half-life of only 12 minutes due to rapid degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), exendin-4 exhibits resistance to DPP-4 breakdown

The REWIND study evaluated the cardiovascular safety of dulaglutide (1.5 mg) in comparison to placebo ( Exenatide The EXSCEL (Exenatide Study of Cardiovascular Event Lowering) trial evaluated the CV safety of exenatide (2 mg weekly)