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This approach has philosophical appeal for those seeking to optimize underlying biology rather than override it
There have also been reports of non-insulinotropic effects of GLP- 1 receptor activation
When it might shine If youre in a setting where you want more acute, measurable shifts in sleep architecture (for example, significantly enhancing delta wave sleep or improving very poor sleep quality) and youre comfortable with injections, then DSIP via injection might make sense
However many of these have off-target toxicity, low specificity, or are in early stages
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