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Alpha lipoic acid, a naturally occurring dithiol compound which plays an essential role in mitochondrial bioenergetic reactions, has gained considerable attention as an antioxidant for use in managing diabetic complications

e.g., under nutrient starvation, being able to provide substrates for ATP production and macromolecule synthesis (Zhang, 2013)

Additionally, NAD+ supplements have shown some benefits in treating and preventing some neurodegenerative diseases such as Alzheimer's disease

Herbal Medicine: An Introduction to Its History, Usage, Regulation, Current Trends, and Research Needs, in Herbal Medicine: Biomolecular and Clinical Aspects