Mucosal involvement occurs in up to 90% of patients, and mouth ulcers, grittiness in the eyes, odynophagia, and dysuria are common
In addition, after the initial depletion of GSH by oxidants such as H 2 O 2 , redox recycling, menadione, and hyperoxia, there is also a later increase in GSH at 1224 h in lungs in vivo and in human alveolar and bronchial epithelial and endothelial cells in vitro (96, 108, 191)
[2] [8] However, the agency noted they cannot definitively rule out that a small risk may exist and continues to review incoming safety reports through the FDA Adverse Event Reporting System (FAERS) and other surveillance mechanisms
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