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Severe hypersensitivity reactions, including anaphylaxis, generalized urticaria, and hypotension, tachycardia, and bronchospasm, have been reported following local instillation or injection of methylene blue

The reasons for this arent totally clear for instance, there are more young adults living with their parents these days (a potential buzzkill, depending on the circumstances)

The agency advises consumers to: Only use medicines that have been prescribed by a registered healthcare professional and dispensed by a regulated pharmacy

This means you likely won't see a visible shift in your complexion for at least a month or two of consistent use