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Moreover, scars can progress pathologically into hypertrophic scars and keloids characterized by uncontrolled fibroproliferation, the continuous accumulation of ECM and cells, and, in the case of keloids, invasion of adjacent healthy skin [150, 153, 154]
i , Immunoblot analysis of SYVN1 from SLC33A1 -knockout HEK293T cells complemented with a vector control or SLC33A1 cDNA expressing sgRNA targeting intergenic region or two different sgRNAs targeting SYVN1
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