GHK-Cu exerts broad anti-inflammatory effects through its influence on approximately 31% of the human genome, specifically downregulating genes involved in inflammatory processes including interleukin-1, tumor necrosis factor-, and nuclear factor-B (NF-B) signaling while upregulating protective genes encoding antioxidant enzymes, DNA repair proteins, and anti-inflammatory mediators
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doi:10.1016/j.biopha.2018.04.003 [86] Alok S, Jain SK, Verma A, Kumar M, Mahor A, Sabharwal M