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Lab Investig
j-k , Serum tGSH (no tumor vs
Licensed recombinant human growth hormone (somatropin) is available on the NHS for confirmed GH deficiency in both children and adults, subject to NICE criteria
In hepatocellular carcinoma (HCC) cells, post-translational activation of cystathionine -synthase (CBS) under TNF-induced oxidative stress increases TSS activity through a proteolytically cleaved and highly active form of CBS, increasing cystathionine and GSH production (102), which in turn promotes tumor progression and inhibits ferroptosis
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