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Wadden TA, Hollander P, Klein S, Niswender K, Woo V, Hale PM et al (2013) Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: the SCALE Maintenance randomized study

However, research models consistently demonstrate that single GLP-1 agonists like Sema also produce concurrent loss of lean muscle mass alongside fat mass