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Human evidence for precursors is mixed: some trials report good safety, but metabolic endpoints such as insulin sensitivity have not consistently replicated in people
the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor
Lip-C injections are not a substitute for diet, exercise, or prescription weight loss medications when indicated
& Abeles, R
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