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The DNAPK complex also serves as a key regulator of hyperglycemia-induced endothelial ferroptosis in T2DM cardiomyopathy, potentially representing a novel therapeutic strategy to alleviate T2DM microvascular dysfunction and cardiac dysfunction [97]
ROS/MAPKs/nuclear transcription factor-kappa B (NF-B)/NLRP3 activation causes osteoclast-mediated bone loss in diabetic osteoporosis (73)
Studies have indicated that supplementing with Vitamin B12 may help improve cognitive function, behavior, and overall mood in individuals with ASD
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