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2.2.3 Regulatory role of intestinal excretion Quantitative contribution: Using C14 tracer studies, Sorensen (1965) demonstrated that a significant portion of total body uric acid turnover (1/3) is excreted via the intestine (extrarenal elimination pathway) compared to 2/3 excreted renally ( 2.2.4 Mechanisms of renal and intestinal urate reabsorption and excretion Renal and intestinal handling of urate relies on specific transporters to maintain systemic urate levels

This testing may be required to assess the performance of the device in a tropical climate or to assess the safety of the device for use by the Singapore population

Antioxidant Defense: Magnesium itself has antioxidant properties, helping to protect cells from oxidative stress

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