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Cagrilintide as a standalone medication is earlier in development, so an individual approval is likely further out, possibly 2028 or beyond

TB-500, a synthetic fragment derived from thymosin beta-4, has been studied for its role in cellular migration, cytoskeletal organization, angiogenesis, and tissue regeneration

Achieved IgG reduction is similar to that achieved by nipocalimab in human FcRn transgenic mice [360], and a concomitant therapeutic effect has been observed in animal models of arthritis, ITP and glomerulonephritis [414,415,416] and in clinical trials assessing safety (NCT01802697), increasing transplant success by negating pre-existing immunity (NCT02224820, NCT02426684, and NCT02475551), and in thrombotic thrombocytopenic purpura (NCT02854059)