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Glucocorticoids inhibit fructose 2,6-bisphosphate synthesis in rat thymocytes
Therefore, future prospective studies with standardized protocols for C-peptide measurement are warranted to further elucidate the pathophysiology of SGLT2 inhibitor-associated DKA
The review states that a definitive link could not be confirmed due to insufficient information about possible confounders such as pre-existing mental health problems, family history, life stressors, social and environmental factors, and use of other medications with labelling related to suicidality
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