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The 4 stages of B12 deficiency include (31): Stage 1: decreased levels of vitamin B12 in your blood Stage 2: low levels of vitamin B12 in your cells along with metabolic abnormalities Stage 3: neurological and psychological symptoms like anxiety, confusion, problems with balance, and others Stage 4: macrocytic anemia very large red blood cells (32) B12 deficiency can cause a variety of symptoms, including fatigue, headaches, depression, pale or yellow skin, mental impairment, and pain and inflammation in the mouth and tongue
Do not wait for routine labs Fever, bloody stool, severe abdominal pain, spreading rash, jaundice, allergic symptoms, or severe wound changes need medical review
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Timing and Frequency Considerations: AOD-9604 is most commonly administered once daily in the morning on an empty stomach to maximize absorption and align with natural circadian metabolic rhythms
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