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doi:10.1016/S0736-0266(03)00110-4 Bock-Marquette I, Saxena A, White MD, DiMaio JM, Srivastava D
Interestingly, pretreatment with the GHSR inverse agonist SP-analog enhances 5-HT 2C intracellular receptor signaling, supporting the notion that inverse agonists of the GHSR (and perhaps antagonists) may augment the effectiveness of 5-HT 2C in the treatment of schizophrenia
The initial dosage begins at 0.6 mg and increases by 0.6 mg weekly until the target of 3 mg daily is achieved
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