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Furthermore, intestinal dysbiosis may independently contribute to metabolic dysregulation
These applications span acute diarrheal diseases, IBS, a variety of bacterial and viral infections (including HIV and HPV), obesity, insulin resistance syndrome, type 2 diabetes, NAFLD, cancer, allergic disorders, neurological conditions, and lactose intolerance (342, 343)
Elevated phospholipid concentrations with concomitant lower choline, elevated medium-chain acylcarnitines (MC-AC), and decreased ratios of MC-AC and long-chain (LC)-AC were associated with prednisolone medication
These LCACs enhance the ability of RAW264.7 cells to phagocytose lipids by upregulating macrophage receptor with collagenous structure (MARCO), thereby aggravating the accumulation of intracellular lipids, which promotes the formation of foam cells and accelerates the development of atherosclerosis [228]
