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The full 12-week, three-phase cycle remains the baseline rather than compressing the protocol into eight weeks
46 In rat model of OA, the nuclear localization of Nrf2 enhanced by Transient Receptor Potential Vanilloid (TRPV)-1 activation via the Ca 2+ /calmodulin-dependent protein kinase II (CaMKII)/Nrf2 signaling pathway inhibited M1 macrophage polarization in synovium, thus attenuating OA progression
Stay Hydrated and Support Overall Health: Adequate hydration, balanced nutrition, and proper rest can optimize the healing process
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