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doi: 10.2147/DDDT.S82030

Thus, in terms of development of transporter-utilizing prodrugs for delivery to the brain, it is essential to understand the mechanism of BBB permeation, intra-brain distribution and release of parent drug from prodrug at the target site within the brain (Fig

The committees recommendations are non-binding, but they often shape what the FDA later allows compounding pharmacies to prepare for patients