Glucagon-like peptide 1 is a hormone the human body naturally secretes in the small intestine, triggering the pancreas to release insulin, which regulates blood sugar and allows the body to convert food into energy
N Engl J Med 373:22472257 Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB (2016) LEADER Steering Committee
Expression of GLP-1R in RIN-5F, a rat insulinoma-derived pancreatic -cell line
2.6.6.2 Klotho and GH secretion Although klotho was identified in 1997 as an antiaging agent, klotho-deficient mice exhibit growth retardation [204], implying that this transmembrane protein is also involved in the control of GH secretion