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It binds exclusively to GLP-1 receptors, modulating gastric motility, insulin secretion, and central satiety signaling

Rest and hydration are key to managing these symptoms

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Calibrate, which began prescribing anti-obesity medications in 2020 as part of a weight loss program, prominently describes the drugs as a temporary aid to improve your metabolic health. In Denmark, a venture-backed startup, Embla, says on its website that it offers GLP-1s always with the clear aim of a healthy transition off medication once youve reached your goals. (Other companies, including the weight-loss giant WeightWatchers and more recent incumbents such as Ro, have begun dabbling in GLP-1 medications, too, though they are clear in their messaging that these drugs are meant to be taken long-term.) A spokeswoman for Noom frames the issue as partly one of customer demand: When asked about the companys marketing of Ozempic as a drug to take for a limited time, she emphasized that most patients dont want to stay on the medications forever, noting that research showing that 68% of people stop taking the GLP-1 by month 12 suggests a reticence to a forever medication by many