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It targets tumor cells and inhibits tumor progression by reducing the production of 2-hydroxyglutarate (2-HG) mediated by isocitrate dehydrogenase 1 (IDH1mt) ( 4.2.2 Targeting Gln-related metabolic enzymes In addition to Gln uptake inhibitors, enzymes involved in Gln metabolism also play a crucial role in tumor progression

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Helps regulate metabolic activity and energy expenditure